Hourou Musuko

Name: Hourou Musuko
Genre: Animation, Drama
Released: 2011
Rating: 8.5
Cast: Hatakeyama Kousuke, Asami Seto, Yuka Nanri, Yoshino Nanjo, Yûichi Iguchi

Yoshino and Shuichi are two friends, both starting at a new school, both starting puberty, and both transgender. This series follows them as they come out and find acceptance.